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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DSP All Species: 10
Human Site: S2572 Identified Species: 27.5
UniProt: P15924 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15924 NP_001008844.1 2871 331774 S2572 N G V G T S S S M G S G V S D
Chimpanzee Pan troglodytes XP_518227 2871 331691 S2572 N G V G T S S S M G S G V S D
Rhesus Macaque Macaca mulatta XP_001085012 2871 331645 S2572 N G V G T S S S M G S G V S D
Dog Lupus familis XP_545329 2280 261115 S1994 F S N S R H E S L S K I S T I
Cat Felis silvestris
Mouse Mus musculus Q9QXS1 4691 534197 A4377 T L S I T E F A D M L S G N A
Rat Rattus norvegicus P30427 4687 533521 A4373 T L S I T E F A D M L S G N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514169 2826 326275 V2530 S I K N G G G V G V G G A G D
Chicken Gallus gallus XP_418957 2861 330750 D2572 I S C R N G T D E V F R H E S
Frog Xenopus laevis Q9PTD7 1360 158447 Q1074 Q F N S S R M Q E E V Q K L K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.7 76.3 N.A. 27.7 27.4 N.A. 89.6 76.9 20.3 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 99.5 78 N.A. 43.5 43.2 N.A. 94.8 88.6 32.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 6.6 6.6 N.A. 13.3 0 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 20 20 N.A. 20 6.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 23 0 0 0 0 12 0 23 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 23 0 0 0 0 0 45 % D
% Glu: 0 0 0 0 0 23 12 0 23 12 0 0 0 12 0 % E
% Phe: 12 12 0 0 0 0 23 0 0 0 12 0 0 0 0 % F
% Gly: 0 34 0 34 12 23 12 0 12 34 12 45 23 12 0 % G
% His: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 0 % H
% Ile: 12 12 0 23 0 0 0 0 0 0 0 12 0 0 12 % I
% Lys: 0 0 12 0 0 0 0 0 0 0 12 0 12 0 12 % K
% Leu: 0 23 0 0 0 0 0 0 12 0 23 0 0 12 0 % L
% Met: 0 0 0 0 0 0 12 0 34 23 0 0 0 0 0 % M
% Asn: 34 0 23 12 12 0 0 0 0 0 0 0 0 23 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 0 0 0 12 0 0 0 12 0 0 0 % Q
% Arg: 0 0 0 12 12 12 0 0 0 0 0 12 0 0 0 % R
% Ser: 12 23 23 23 12 34 34 45 0 12 34 23 12 34 12 % S
% Thr: 23 0 0 0 56 0 12 0 0 0 0 0 0 12 0 % T
% Val: 0 0 34 0 0 0 0 12 0 23 12 0 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _